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The sequence encoding hexa-Gly residues was generated downstream of the sequence of AsGGT1 , AsGGT2 , and AsGGT3 by the PCR

These hydrophobic residues form a patch that might be necessary to hold the X helix in place

Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells

Both proteins are involved in how cells response to damage and stress, but were so far mostly considered to have separate biological roles

Fortunately, iodine deficiency is easy to treat, as long as it is diagnosed properly

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