Histone H4 (Di Methyl Lys59) Polyclonal Antibody, 100ul Yeast Expression The protein primarily localizes to

The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface

GO annotations related to this gene include actin binding and kinesin binding

This gene forms the basis for the Kidd blood group system

and may play an important role in nervous system development

and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation

Histone H4 (Di Methyl Lys59) Polyclonal Antibody, 100ul Yeast Expression The protein primarily localizes toHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.