ACSL1 Polyclonal Antibody, 20ul Organelle Studies Survival factors can suppress apoptosis

Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1

Belongs to the dynactin subunit 4 family

It requires divalent metal ions and an intact Nudix motif for enzymatic activity

domain:The C1 domain does not bind the diacylglycerol (DAG)

The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradatio

ACSL1 Polyclonal Antibody, 20ul Organelle Studies Survival factors can suppress apoptosisThe protein encoded by this gene is an isozyme of the long chain fatty acid coenzyme A ligase family. Although differing in substrate specificity subcellular localization and tissue distribution all isozymes of this family convert free long chain fatty acids into fatty acyl CoA esters and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene.