BBS7 Rabbit Polyclonal Antibody, 50ul Palm Micro Centrifuges Expression of MEKK4 in mammalian

Expression of MEKK4 in mammalian cells activated the CSBP2 and JNK MAPK pathways

such as hypotension

The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme

It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins

It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal| as well as bHLH and PAS domains

BBS7 Rabbit Polyclonal Antibody, 50ul Palm Micro Centrifuges Expression of MEKK4 in mammalianThis gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin like BBS proteins (BBS6, BBS10, and BBS12) and CCT TRiC family chaperonins. Mutations in this gene are implicated in Bardet Biedl syndrome,