Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Each of the three genes

Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein

They physically associate with both proteasomes and ubiquitin ligases

and is thought to play a role in the early stage of recombinational repair of DNA

The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein

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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Each of the three genesBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal