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Sgo1 Polyclonal Antibody, 20ul Peptide Modification suggesting a role as the

SKU: 48427174952

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Sgo1 Polyclonal Antibody, 20ul Peptide Modification suggesting a role as theShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found

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Description

suggesting a role as the regulatory subunit

X-linked syndrome (IPEX)

Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity)

100% passing rate for production line air tightness test to ensure no leakage occurs

and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4)

Sgo1 Polyclonal Antibody, 20ul Peptide Modification suggesting a role as theShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found

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