PR23C Rabbit Polyclonal Antibody, 100ul Metabolic enzymes Contains 1 N-terminal Ras-GEF domain

Contains 1 N-terminal Ras-GEF domain

The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors| inositol 1|4|5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling| T-cell activation and trafficking of amyloid beta peptides

This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa

This gene is found in a cluster with other desmoglein family members on chromosome 18

an autosomal recessive chromosomal instability syndrome characterized by microcephaly

PR23C Rabbit Polyclonal Antibody, 100ul Metabolic enzymes Contains 1 N-terminal Ras-GEF domain