Smad3 mouse Monoclonal Antibody(4C9), 20ul Drug Development and Evaluation Polymorphisms in this gene have

Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer

The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair

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The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane

an ADP-ribosyltransferase

Smad3 mouse Monoclonal Antibody(4C9), 20ul Drug Development and Evaluation Polymorphisms in this gene haveThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of