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IL-10R Alpha Polyclonal Antibody, 20ul[BT-AP04430] Polyclonal Antibodies Several transcript variants encoding two

SKU: 47720627489

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IL-10R Alpha Polyclonal Antibody, 20ul[BT-AP04430] Polyclonal Antibodies Several transcript variants encoding twoInterleukin 10 receptor subunit alpha encoded by IL10RA is a receptor for interleukin 10. Interleukin 10 receptor subunit alpha is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate 2 PI 3 kinase AKT pathway.

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Description

Several transcript variants encoding two different isoforms have been found for this gene

Growth factor receptor-bound protein 10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules

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Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development

IL-10R Alpha Polyclonal Antibody, 20ul[BT-AP04430] Polyclonal Antibodies Several transcript variants encoding twoInterleukin 10 receptor subunit alpha encoded by IL10RA is a receptor for interleukin 10. Interleukin 10 receptor subunit alpha is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate 2 PI 3 kinase AKT pathway.

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