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MDM2 Polyclonal Antibody, 50ul[BT-AP05301] Drug Development and Evaluation This protein regulates Myotonic Dystrophy

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MDM2 Polyclonal Antibody, 50ul[BT-AP05301] Drug Development and Evaluation This protein regulates Myotonic DystrophyMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many

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Description

This protein regulates Myotonic Dystrophy Protein Kinase

neural tube defects

Serine/threonine-protein kinase mTOR encoded by MTOR belongs to a family of phosphatidylinositol kinase-related kinases

The signal transduction of this receptor is mediated by various death domain containing adaptor proteins

|disease:A chromosomal aberration involving CCND1 may be a cause of multiple myeloma

MDM2 Polyclonal Antibody, 50ul[BT-AP05301] Drug Development and Evaluation This protein regulates Myotonic DystrophyMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many

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