CEP55(Phospho Ser425) Polyclonal Antibody, 50ul Plates & Dishes Ceramide hydrolysis in the nucleated

Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress

|PTM:Autophosphorylated on Ser-377| as part of the activation process

differs at the C-terminal end

Transcription factor EB (TFEB) is a member of the Myc-related

DOR-1 and KOR-1

CEP55(Phospho Ser425) Polyclonal Antibody, 50ul Plates & Dishes Ceramide hydrolysis in the nucleatedPlays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis.,PTM: There is a hierachy of phosphorylation, where both Ser 425 and Ser 428 are phosphorylated at the onset of mitosis, prior to Ser 436. Phosphorylation at Ser 425 and Ser 428 is required for dissociation from the centrosome at the G2 M boundary. Phosphorylation at the 3 sites, Ser 425, Ser 428 and Ser 436,