Phospho-AP-1 (Y170) Polyclonal Antibody, 50ul General Lab Use The encoded protein is a

The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II

Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D)

PTM:Phosphorylated by GRK6 upon leukotriene B4 binding

The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state

Eight transcript variants encoding the same protein have been found for this gene

Phospho-AP-1 (Y170) Polyclonal Antibody, 50ul General Lab Use The encoded protein is aJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.