His-Tag Polyclonal Antibody, 20ul[BT-AP09900] Custom DNA Oligos Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding three distinct isoforms have been reported

the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions

The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis

EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein

suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress

His-Tag Polyclonal Antibody, 20ul[BT-AP09900] Custom DNA Oligos Several alternatively spliced transcript variantsA polyhistidine tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N or C terminus of the protein. It is also known as hexa histidine tag, 6xHis tag, and by the trademarked name His tag. Polyhistidine tags are often used for affinity purification of polyhistidine tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.