PAK alpha(Phospho Ser199) Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene are

Mutations in this gene are associated with microphthalmia

Found in a complex with XPO7| EIF4A1| ARHGAP1| VPS26A| VPS29| VPS35 and SFN

This protein may play a role in maintaining the differentiated state of muscle cells

1993 [PubMed 8224848])

and thus induce the nuclear production of NF-kappaB

PAK alpha(Phospho Ser199) Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene areThis gene encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this