Collagen IV Polyclonal Antibody, 20ul[BT-AP15068] Pipette Filler Unlike the other two isoforms|

Unlike the other two isoforms| p46Shc is targeted to the mitochondrial matrix

|subcellular location:Associated with the mitochondrial membrane

The protein promotes entry into S phase

a disease characterized by abnormalities in cartilage and bone development

Cleaves caspase-1

Collagen IV Polyclonal Antibody, 20ul[BT-AP15068] Pipette Filler Unlike the other two isoforms|This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino terminal 7S domain, a triple helix forming collagenous domain, and a carboxy terminal non collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components