CGL Polyclonal Antibody, 100ul Lysosome Apoptosis induction involves sequestration of

Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC

It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin

or fibronectin

Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover

An important paralog of this gene is MAP4K3

CGL Polyclonal Antibody, 100ul Lysosome Apoptosis induction involves sequestration ofThis gene encodes a cytoplasmic enzyme in the trans sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.