CP51A Polyclonal Antibody, 20ul Dry Bath Mutations in PSAP have been

Mutations in PSAP have been associated with Gaucher disease and metachromatic leukodystrophy

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Expression is upregulated by retinoic acid in a human teratocarcinoma cell line

Related pseudogenes have been identified on chromosomes 3 and 10

Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases

CP51A Polyclonal Antibody, 20ul Dry Bath Mutations in PSAP have beenThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi,