MARCH4 Polyclonal Antibody, 100ul Buffers & Solutions Higher expression levels of RPS19

Higher expression levels of RPS19 in some primary colon carcinomas compared to matched normal colon tissues has been observed

this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas

respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins

The ligand for c-mpl| thrombopoietin| was cloned in 1994

amino terminal (UBA) domains and one ubiquitin-specific processing protease (UBP) domain

MARCH4 Polyclonal Antibody, 100ul Buffers & Solutions Higher expression levels of RPS19MARCH4 is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment.