RPIA Rabbit Polyclonal Antibody, 20ul Live Cell Imaging The protein encoded by MAP3K1

The protein encoded by MAP3K1 (mitogen-activated protein kinase kinase kinase 1) is a serine/threonine kinase and is part of some signal transduction cascades

and is subject to RNA editing (AGA->GGA| R->G)

The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes

Synaptotogmin family members can form homo- and heteromeric complexes with each other

Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations

RPIA Rabbit Polyclonal Antibody, 20ul Live Cell Imaging The protein encoded by MAP3K1The protein encoded by this gene is an enzyme which catalyzes the reversible conversion between ribose 5 phosphate and ribulose 5 phosphate in the pentose phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5 phosphate isomerase deficiency. A pseudogene is found on chromosome 18.