PDE4B/C/D(Phospho Ser133/119/190) Polyclonal Antibody, 100ul Adenovirus Packaging Selectively inhibits the phosphatase activity

Selectively inhibits the phosphatase activity of PPP1C

This gene product may play a dual role in regulating CDK and RNA polymerase II activities

and is located within the NIDDM1 region

It transduces signals from CRK by binding the SH3 domain of CRK

q21) is associated with familial clear cell renal cancer

PDE4B/C/D(Phospho Ser133/119/190) Polyclonal Antibody, 100ul Adenovirus Packaging Selectively inhibits the phosphatase activityThis gene is a member of the type IV, cyclic AMP (cAMP) specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding