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MKL2 Polyclonal Antibody, 20ul Culture Media Component of the core-TFIIH basal

SKU: 44658017283

4.1
USD97.20 USD136.20

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MKL2 Polyclonal Antibody, 20ul Culture Media Component of the core-TFIIH basalThe N terminal region is required for nuclear localization and the C terminal region mediates transcriptional activity.,Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.,PTM: O glycosylated.,Contains 1 SAP domain.,Contains 3 RPEL repeats.,subunit: Interacts with MKL1 and SRF.,

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Description

Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and

This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls| which implicated the role in neurodegenerative diseases

The kinase exists as a tetramer and is composed of an alpha

these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway

The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli

MKL2 Polyclonal Antibody, 20ul Culture Media Component of the core-TFIIH basalThe N terminal region is required for nuclear localization and the C terminal region mediates transcriptional activity.,Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.,PTM: O glycosylated.,Contains 1 SAP domain.,Contains 3 RPEL repeats.,subunit: Interacts with MKL1 and SRF.,

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