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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07022] Nucleic Acid Amplification somatic and familial gastrointestinal stromal

SKU: 44327785857

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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07022] Nucleic Acid Amplification somatic and familial gastrointestinal stromalPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

somatic and familial gastrointestinal stromal tumors

This gene is expressed primarily in the placenta and ovarian granulosa cells

DVL2 and/or DVL3)

Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation| type IIk

BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2

PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07022] Nucleic Acid Amplification somatic and familial gastrointestinal stromalPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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