LSM1 Polyclonal Antibody, 100ul Glassware Mutations in RRM2B have been

Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome

Dok-3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B cells and macrophages

It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP

Typing for these polymorphisms is routinely done for bone marro

Individual members of this family differ in the number of C-terminal TS motifs

LSM1 Polyclonal Antibody, 100ul Glassware Mutations in RRM2B have beenThis gene encodes a member of the LSm family of RNA binding proteins. LSm proteins form stable heteromers that bind specifically to the 3' terminal oligo(U) tract of U6 snRNA and may play a role in pre mRNA splicing by mediating U4 U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced