PA21B Polyclonal Antibody, 100ul 3D Cell Culture Consumables The encoded protein is expressed

The encoded protein is expressed in the cytoplasm and has a preference for galactose

Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers

2006 [PubMed: 16426570])

PTM:The disulfide bond may lock the enzyme in a closed conformation under oxidized conditions

Several alternatively spliced transcript variants of DMPK have been described

PA21B Polyclonal Antibody, 100ul 3D Cell Culture Consumables The encoded protein is expressedThis gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium dependent enzyme catalyzes the hydrolysis of the sn 2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs)