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GUF1 Polyclonal Antibody, 100ul Buffer Solutions This protein is deleted in

SKU: 43867629318

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GUF1 Polyclonal Antibody, 100ul Buffer Solutions This protein is deleted inGUF1 (GUF1 GTPase), also known as EF 4 (elongation factor 4 homolog), is a 669 amino acid protein belonging to the GTP binding elongation factor family and the LepA subfamily. Localizing to the mitochondrion inner membrane, GUF1 promotes mitochondrial protein synthesis and binds to mitochondrial ribosomes in a GTP dependent manner. GUF1 may act as a fidelity factor of the translation reaction, by catalyzing a one codon backward translocation of tRNAs

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Description

This protein is deleted in some patients with Wilms tumor-Aniridia-Genitourinary anomalies-mental Retardation (WAGR) syndrome

This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite| L-kynurenine| to form L-3-hydroxykynurenine

which recycles the EIF-2 complex for another round of initiation

There are two known clusters of MAGE genes on chromosome X

It functions as a repressor of TGF-beta signaling

GUF1 Polyclonal Antibody, 100ul Buffer Solutions This protein is deleted inGUF1 (GUF1 GTPase), also known as EF 4 (elongation factor 4 homolog), is a 669 amino acid protein belonging to the GTP binding elongation factor family and the LepA subfamily. Localizing to the mitochondrion inner membrane, GUF1 promotes mitochondrial protein synthesis and binds to mitochondrial ribosomes in a GTP dependent manner. GUF1 may act as a fidelity factor of the translation reaction, by catalyzing a one codon backward translocation of tRNAs

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