PSME1 Rabbit Polyclonal Antibody, 100ul Cryopreservation Four alternatively spliced transcript variants

Four alternatively spliced transcript variants encoding the same protein exist for this gene

It is uncertain whether Met-1 or Met-6 is the initiator

The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions

Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed

and auditory defects

PSME1 Rabbit Polyclonal Antibody, 100ul Cryopreservation Four alternatively spliced transcript variantsThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base which contains 6 ATPase subunits and 2 non ATPase subunits and a lid which contains up to 10 non ATPase subunits.