BMAL1 Monoclonal Antibody, 100ul Drying & Desiccation Mutations in this gene are

Mutations in this gene are associated with Griscelli syndrome type 2

However| in human| the single gene with sequence similarity to TDH is not capable of encoding a functional TDH protein

This gene encodes a DEAD box protein| which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression

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The protein encoded by this gene is a nuclear matrix protein

BMAL1 Monoclonal Antibody, 100ul Drying & Desiccation Mutations in this gene areThe protein encoded by this gene is a basic helix loop helix protein that forms a heterodimer with CLOCK. This heterodimer binds E box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK ARNTL complexes. Defects in this gene have been linked to