SGIP1 Rabbit Polyclonal Antibody, 20ul Vessels RBR E3 ubiquitin protein ligase

RBR E3 ubiquitin protein ligase contains two RING-finger motifs and an in between RING fingers motif

The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair

and single nucleotide polymorphisms in this gene are associated with blood pressure variation

and an unprocessed pseudogene has been found on chromosome 10

Alternatively spliced transcript variants encoding different isoforms have been found for this gene

SGIP1 Rabbit Polyclonal Antibody, 20ul Vessels RBR E3 ubiquitin protein ligaseSGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al. 2005