PMS2/PMS2CL Polyclonal Antibody, 50ul Cell Screening and Imaging The encoded protein is thought

The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4

which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al

This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level

Defects in ARNTL have been linked to infertility

Present in T-cells but not B-cells (at protein level)

PMS2/PMS2CL Polyclonal Antibody, 50ul Cell Screening and Imaging The encoded protein is thoughtThe protein encoded by PMS2 (PMS1 homolog 2, mismatch repair system component) is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL alpha heterodimer. The MutL alpha heterodimer possesses an endonucleolytic