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BMP-2 Polyclonal Antibody, 50ul[BT-AP00920] Pipette Micro Tips in both virus-infected primary cells

SKU: 43024567622

4.2
PLN185.00 PLN228.00

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BMP-2 Polyclonal Antibody, 50ul[BT-AP00920] Pipette Micro Tips in both virus-infected primary cellsBMP2 (bone morphogenetic protein 2) encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer, which plays a role in bone and cartilage

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Description

in both virus-infected primary cells and in cells transfected with plasmids that express N protein

bioactivity

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways

Finally| hypermethylation of this gene may find usefulness as a biomarker for gastric cancer

BMP-2 Polyclonal Antibody, 50ul[BT-AP00920] Pipette Micro Tips in both virus-infected primary cellsBMP2 (bone morphogenetic protein 2) encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer, which plays a role in bone and cartilage

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