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PTEN Polyclonal Antibody, 50ul[BT-AP07473] Pasteur Pipets An important paralog of this

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PTEN Polyclonal Antibody, 50ul[BT-AP07473] Pasteur Pipets An important paralog of thisPTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. Pphosphatase and tensin homolog encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, t phosphatase and tensin homolog preferentially

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Description

An important paralog of this gene is UBA52

probable scaffold protein that may be involved in mRNA transport

This protein localizes with a speckled pattern in the nucleus

|pharmaceutical:A constitutively active FOXO4 mutant where phosphorylation sites Thr-32| Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival| transformation and tumorigenicity

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PTEN Polyclonal Antibody, 50ul[BT-AP07473] Pasteur Pipets An important paralog of thisPTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. Pphosphatase and tensin homolog encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, t phosphatase and tensin homolog preferentially

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