Histone H2A.Z (Acetyl Lys14) Rabbit Polyclonal Antibody, 50ul Culture Plate Inserts May act downstream of P38-kinase

May act downstream of P38-kinase and BCL-2

Multiple spliced transcript variants have been found for this gene

and may play a role in cell interactions with the extracellular matrix

It belongs to the creatine kinase isoenzyme family

Increases p53/TP53-dependent transcription and apoptosis

Histone H2A.Z (Acetyl Lys14) Rabbit Polyclonal Antibody, 50ul Culture Plate Inserts May act downstream of P38-kinaseVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone