Neurofibromin Polyclonal Antibody, 100ul Capsule Filter Location-regulated scaffolding protein connecting MEK
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Neurofibromin Polyclonal Antibody, 100ul Capsule Filter Location-regulated scaffolding protein connecting MEKNF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA >Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.
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