Vav(Phospho Tyr174) Polyclonal Antibody, 100ul NGS Oligos Members of this family are

Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions

1-10μl volumes

The SFPQ-NONO/SF-1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity

Autoantibodies against this protein have been found in patients with cancer or graft versus host disease

also known as neuralized-like protein 4

Vav(Phospho Tyr174) Polyclonal Antibody, 100ul NGS Oligos Members of this family areThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.