Actinin- Alpha2 Monoclonal Antibody, 50ul Serological Pipets Mutations in this gene have

Mutations in this gene have been linked to cryptogenic cirrhosis

contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 Lys-9 trimethylation

The function of RASSF4 has not yet been determined but may involve a role in tumor suppression

thus leading to cohesin dephosphorylation (By similarity)

2002 [PubMed 11784320])

Actinin- Alpha2 Monoclonal Antibody, 50ul Serological Pipets Mutations in this gene haveAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac,