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CD6 Polyclonal Antibody, 50ul[BT-AP02137] Cell Proliferation some of which are candidates

SKU: 42309932882

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CD6 Polyclonal Antibody, 50ul[BT-AP02137] Cell Proliferation some of which are candidatesThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase

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Description

some of which are candidates for nonsense-mediated mRNA decay (NMD)

and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma

thereby inhibiting the processes that trigger oncogenic transformation

which bridge between the doublet microtubules in axonemes

subcellular location:Distribution is cell cycle-modulated

CD6 Polyclonal Antibody, 50ul[BT-AP02137] Cell Proliferation some of which are candidatesThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase

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