c-Fms(Phospho Tyr723) Polyclonal Antibody, 20ul Electrophoresis & Labeling using magnesium as a cofactor

using magnesium as a cofactor

TAF1 (TATA-box binding protein associated factor 1) encodes the largest subunit of TFIID

This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes

It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases

The upstream promoter is located in a differentially methylated region (DMR) and undergoes imprinting

c-Fms(Phospho Tyr723) Polyclonal Antibody, 20ul Electrophoresis & Labeling using magnesium as a cofactorThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF