GCN2 Polyclonal Antibody, 100ul Subcellular Fractions and functions in transcriptional repression

and functions in transcriptional repression of homeotic genes

manifested as goiter

which synthesizes small RNAs

The protein encoded by this gene mediates calcium entry| and this entry is potentiated by calcium store depletion

including overexpression

GCN2 Polyclonal Antibody, 100ul Subcellular Fractions and functions in transcriptional repressionEIF2AK4 encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 (EIF2), resulting in the down regulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary