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RN123 Polyclonal Antibody, 50ul Antibody Development Transcriptional repression by the encoded

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RN123 Polyclonal Antibody, 50ul Antibody Development Transcriptional repression by the encodedThe protein encoded by this gene contains a C terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein protein and protein DNA interactions, and an N terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants.

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Description

Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex

Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation

30-300 µl

May regulate osteoblast proliferation and differentiation

called PPARs

RN123 Polyclonal Antibody, 50ul Antibody Development Transcriptional repression by the encodedThe protein encoded by this gene contains a C terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein protein and protein DNA interactions, and an N terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants.

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