RN123 Polyclonal Antibody, 50ul Antibody Development Transcriptional repression by the encoded
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RN123 Polyclonal Antibody, 50ul Antibody Development Transcriptional repression by the encodedThe protein encoded by this gene contains a C terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein protein and protein DNA interactions, and an N terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants.
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