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A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia

APC Polyclonal Antibody, 20ul[BT-AP00507] Sample Library Tubes Dare to push the boundariesAPC encodes a tumor suppressor protein (APC, WNT signaling pathway regulator) that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in APC cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a