Rat C-Reactive Protein, CRP ELISA Kit, 96T Bottle-Top Dispenser Negatively regulates MAP3K5/ASK1 kinase activity

Negatively regulates MAP3K5/ASK1 kinase activity

Three transcript variants encoding different isoforms have been found for this gene

This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription

and host defense

SCF(BTRC) directs ubiquitination of NFKBIB

Rat C-Reactive Protein, CRP ELISA Kit, 96T Bottle-Top Dispenser Negatively regulates MAP3K5/ASK1 kinase activityDisplays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity).