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HP-1 Alpha mouse Monoclonal Antibody(5E3), 20ul DNA Oligo Synthesis All GTPases of the Ras

SKU: 4137304833

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PLN111.00 PLN152.00

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HP-1 Alpha mouse Monoclonal Antibody(5E3), 20ul DNA Oligo Synthesis All GTPases of the RasThis gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin associated

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Description

All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding

The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair

Diseases associated with TRAK2 include amyotrophic lateral sclerosis 2

and reduced expression can suppress transforming growth factor-beta induced growth arrest

Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process

HP-1 Alpha mouse Monoclonal Antibody(5E3), 20ul DNA Oligo Synthesis All GTPases of the RasThis gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin associated

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