Smad1/5/9 Polyclonal Antibody, 100ul[BT-AP14289] Molecular Weight Markers Checkpoint kinase 2 encoded by

Checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor

this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH)

The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding

Mutations in this

In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine

Smad1/5/9 Polyclonal Antibody, 100ul[BT-AP14289] Molecular Weight Markers Checkpoint kinase 2 encoded byThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell