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Smad5 Monoclonal Antibody, 50ul[BT-MCA1138] Measuring Instruments This protein has been identified

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Smad5 Monoclonal Antibody, 50ul[BT-MCA1138] Measuring Instruments This protein has been identifiedThe protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

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Description

This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis

composed of both platelet-derived growth factor receptor alpha and beta polypeptides

An important paralog of this gene is MPND

and atherosclerosis

It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients

Smad5 Monoclonal Antibody, 50ul[BT-MCA1138] Measuring Instruments This protein has been identifiedThe protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

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