PCNA Monoclonal Antibody(12D10), 50ul Variant Libraries RBX2 and a variable SOCS

RBX2 and a variable SOCS box domain-containing protein as substrate-specific recognition component

This protein may play a role as a scavenger receptor

and in the prevention of bacterial translocation in the gut

It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation| DNA repair| and/or cell cycle checkpoint control

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein family

PCNA Monoclonal Antibody(12D10), 50ul Variant Libraries RBX2 and a variable SOCSThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have