Cbl Polyclonal Antibody, 50ul[BT-AP01263] Cell fragmentation and collection tissue specificity:Expressed in lung and

tissue specificity:Expressed in lung and macrophages

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2

This gene encodes a protein that contains a leucine zipper motif

It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p

Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain| multiple 8) gene

Cbl Polyclonal Antibody, 50ul[BT-AP01263] Cell fragmentation and collection tissue specificity:Expressed in lung andCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated