RBM8A Rabbit Polyclonal Antibody, 50ul Serum while expression is weak to

while expression is weak to moderate in astrocytomas

Mutations in this gene cause Schwartz-Jampel syndrome type 2

Defects in this gene are a cause of Duane-radial ray syndrome (DRRS)

10) and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias

also known as SDR25C1 or HEP27

RBM8A Rabbit Polyclonal Antibody, 50ul Serum while expression is weak toThis gene encodes a protein with a conserved RNA binding motif. The protein is found predominantly in the nucleus although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present thus coupling pre and post mRNA splicing