DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture This gene is a member

This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye

Multiple alternatively spliced variants have been described for this gene

CREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters

mismatch repair system component forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer

Complex I functions in the transfer of electrons from NADH to the respiratory chain

DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture This gene is a memberThe protein encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and