DU4L7 Rabbit Polyclonal Antibody, 100ul Cell Senescence Growth arrest-specific 1 plays a

Growth arrest-specific 1 plays a role in growth suppression

This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis

Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals

It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses

and thereby terminates insulins activity

DU4L7 Rabbit Polyclonal Antibody, 100ul Cell Senescence Growth arrest-specific 1 plays aThis gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT PCR and in vitro expression