CLCN5 Polyclonal Antibody, 20ul Vortex Mixer beta and gamma subunits are

beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster

These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons

RAF1 and IRS1 proteins

The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates

and Biacore surface resonance analysis

CLCN5 Polyclonal Antibody, 20ul Vortex Mixer beta and gamma subunits areThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.